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KMID : 1161420220250101003
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Journal of Medicinal Food
2022 Volume.25 No. 10 p.1003 ~ p.1010
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Benefits of Flavored Lactose-Free Milk for Korean Adults with Lactose Intolerance
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Oh Chi-Hyuk
Kim Jung-Wook
Park Yoo-Min
Kim Gi-Ae
Jang Jae-Young
Chang Young-Woon
Yang Jin-Oh
Kho Ho-Young
Park Jun-Kyu
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Abstract
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Although lactose-free dairy products for the clinical management of lactose intolerance (LI) are widely available, scientific evidence on their efficacy is still lacking. This study comparatively analyzed the efficacy of flavored lactose-free milk (LFM) and whole milk (WM) in reducing symptoms in South Korean adults with LI. This prospective study was conducted in adults suspected of LI. All screened participants underwent the hydrogen breath test (HBT) using 570?mL of chocolate-flavored WM (20?g of lactose) and responded to a symptom questionnaire. LI was confirmed when the ΔH2 peak exceeded 16?ppm above baseline values and with the occurrence of symptoms after WM consumption. The participants who were diagnosed with LI underwent the HBT again with 570?mL of chocolate-flavored LFM (0?g of lactose), followed by the symptom questionnaire survey after 1 week. After excluding 40 participants who did not meet the diagnostic criteria for LI and 2 who were lost to follow-up, a total of 28 lactose-intolerant individuals were enrolled in the study. The ΔH2 values in the first HBT were significantly higher than those in the second HBT (33.3?±?21.6?ppm vs. 8.6?±?6.3?ppm, P?
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KEYWORD
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lactose intolerance, hydrogen, breath test, milk
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